A portrait of the "SCP/TAPS" proteins of eukaryotes - Developing a framework for fundamental research and biotechnological outcomes

C Cantacessi; BE Campbell; A Visser; P Geldhof; MJ Nolan; AJ Nisbet; JB Matthews; A Loukas; A Hofmann; D Otranto; PW Sternberg; RB Gasser

Journal article

A portrait of the "SCP/TAPS" proteins of eukaryotes - Developing a framework for fundamental research and biotechnological outcomes

C Cantacessi, BE Campbell, A Visser, P Geldhof, MJ Nolan, AJ Nisbet, JB Matthews, A Loukas, A Hofmann, D Otranto, PW Sternberg, RB Gasser

Biotechnology Advances | Published : 2009

DOI: 10.1016/j.biotechadv.2009.02.005

Abstract

A wide range of proteins belonging to the SCP/TAPS "family" has been described for various eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as helminths). Although SCP/TAPS proteins have been proposed to play key roles in a number of fundamental biological processes, such as host-pathogen interactions and defence mechanisms, there is a paucity of information on their genetic relationships, structures and functions, and there is no standardised nomenclature for these proteins. A detailed analysis of the relationships of members of the SCP/TAPS family of proteins, based on key protein signatures, could provide a foundation for investigating these areas. I..

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University of Melbourne Researchers

Andreas Hofmann Author

Robin B. Gasser Author

Related Projects (1)

Discovery of early developmental events in the transition to parasitism in the hookworm Ancylostoma caninum using genomic technologies

The national/community benefits are: (1) to develop a long-term, high quality scientific and technological program contributing to national ..

Grants

Awarded by Australian Government

Funding Acknowledgements

The research was supported by the Australian Research Council (ARC) (DP0665230; RBG and AL), the Australian Academy of Science and the Australian-American Fulbright Commission (RBG). JBM and AJN are funded by the Scottish Government RERAD. CC was the grateful recipient of a Dr Sue Newton Scholarship and an International Postgraduate Research Scholarship (IPRS) from the Australian Government via The University of Melbourne. PG is a Postdoctoral Fellow of the Fund for Scientific Research - Flanders (Belgium) (F.W.C. - Vlaanderen).